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Home / Articles / Free Sports Game Preview and Prediction: Arizona Cardinals vs. San Francisco 49ers (NFL)

Free Sports Game Preview and Prediction: Arizona Cardinals vs. San Francisco 49ers (NFL)

By: Mike Anthony     Date: Nov 6, 2021
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Free Sports Game Preview and Prediction: Arizona Cardinals vs. San Francisco 49ers
Sunday, November 07, 2021 4:25 PM
Play: Point Spread: 2.5/-110 San Francisco 49ers
Jimmy Garoppolo is always willing to do anything and everything to help this team win games. Arizona is going to have their hands full. I like seeing the San Francisco offensive coordinator getting the ball to their TEs and they have a great TE who looks to be coming back in George Kittle. Deebo Samuel has really been coming around for them - especially after his 171 yard game versus Chicago, he has absorbed 10+ targets over 3/5 games - it will be wash, rinse, repeat. He is exuding a lot more confidence. Arizona's Colt McCoy is going to show a bit more pocket mobility, he's not the fastest QB on the field but he will need to move around and create some space. He needs to do this here, or this could snowball. Arizona will be looking like an entirely different team, with Kyler Murray not playing - besides, San Francisco has to show up sometime at home, right? 49ers are 5-2 ATS in their last 7 games as a home underdog San Francisco wins this one on Sunday!
 


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